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Systematic variability in 2 Macedonian family that have Arterial tortuosity syndrome

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Arterial tortuosity disorder (ATS, MIM 208050) try an uncommon autosomal recessive connective tissue disease mainly characterized by elongation and you may tortuosity of one’s highest and medium sized arteries and you can defects of your vascular flexible fabric [1, 2]. Improvements of your vascular morphology and you will structure trigger a propensity to possess aneurysm development and you can vascular dissections, focal and you may/or widespread stenosis of the aorta and you will/or pulmonary bloodstream, and you may vasomotor instability. A cou...

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